LYNNAGEN brings genomic data, clinical context, technical quality and supporting evidence into one reviewable workspace — for clinicians and laboratories who keep the final word.
A profile, a workspace of your own or your laboratory's, the analysis engine, and a report written to be reviewed.
Sign in from any browser. Start a case from a VCF, follow it as it runs, read the worklist, the variant dossier and the clinical report. Invite colleagues to your workspace; turn on two-step sign-in.
Open the workspace →The interpretation engine on the laboratory's own machine: alignment and calling from FASTQ, annotation, 22.8 million indexed evidence records, phenotype fit. Sequencing reads stay in the laboratory; a callset uploaded in the browser is kept only until it is interpreted, and the results are published to the workspace.
Where the data is →Create your profile at no cost. Cases are paid as you go — a number included in your plan each period, more bought in packs when you need them. A case that fails or is cancelled gives its place back.
Create your profile →A clinical report draft that reads each finding against inheritance, phenotype fit and the ACMG secondary-findings list, and says plainly what the analysis does not cover. Final interpretation stays with the reviewing professional.
What stays distinct →Variant pathogenicity, patient relevance, technical quality and evidence provenance are kept apart, so that each can be judged on its own — and the judgment stays with the person signing the report.
Public sources as installed on the analysis workstation; each case records the versions it was read against.
Bring genomic data and case context into a structured workspace.
Validate and prepare variants for interpretation.
Review pathogenicity, patient relevance, technical QC, and supporting evidence together.
Bring the evidence into a clear dossier for clinician or laboratory judgment.
Four questions, answered apart, so that no answer quietly stands in for another.
What is known about the variant itself?
How well does the finding fit the patient and clinical context?
How confident are we in the underlying data?
Where does the supporting evidence come from?
LYNNAGEN helps clinical genetics and diagnostic laboratory teams bring reviewable information to the qualified clinician or laboratory reviewer.
A walk through a case, from the uploaded callset to the report, with your questions.